Optical frequency domain imaging system and catheters for volumetric imaging of the human esophagus

Authors

  • Michalina Gora Wellman Center for Photomedicine, Massachusetts General Hospital and Harvard Medical School
  • Hongki Yoo Wellman Center for Photomedicine, Massachusetts General Hospital and Harvard Medical School
  • Melissa J Suter Wellman Center for Photomedicine, Massachusetts General Hospital and Harvard Medical School
  • Kevin A Gallagher Wellman Center for Photomedicine, Massachusetts General Hospital
  • Brett E Bouma Wellman Center for Photomedicine, Massachusetts General Hospital and Harvard-MIT Division of Health Sciences and Technology
  • Norm S Nishioka Gastrointestinal Unit, Harvard Medical School, Massachusetts General Hospital
  • Guillermo J Tearney Wellman Center for Photomedicine, Massachusetts General Hospital; Harvard-MIT Division of Health Sciences and Technology and Department of Pathology, Harvard Medical School, Massachusetts General Hospital

DOI:

https://doi.org/10.4302/photon.%20lett.%20pl.v3i4.261

Abstract

Barrett's esophagus (BE) is a metaplastic disorder that can undergo dysplastic progression, leading to esophageal adenocarcinoma. Upper endoscopy is the standard of care for screening for BE, but this technique has a relatively low diagnostic accuracy and high cost due to the requirement of conscious sedation. Optical frequency domain imaging (OFDI) is a high-speed imaging modality that generates cross-sectional images of tissues with a resolution of approximately 10µm that is sufficient for detecting microscopic tissue architecture. In combination with a balloon-centering catheter, this method enables BE diagnosis over the entire distal esophagus.  

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References
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Author Biography

Michalina Gora, Wellman Center for Photomedicine, Massachusetts General Hospital and Harvard Medical School

Michalina Gora is a Research Fellow at Wellman Center for Photomedicine, Massachusetts General Hospital and Harvard Medical School. Her research is focused on building a high-speed OFDI system and on developing and testing new cathaters for unsedated gastrointestinal imaging.

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Published

2011-12-29

How to Cite

[1]
M. Gora, “Optical frequency domain imaging system and catheters for volumetric imaging of the human esophagus”, Photonics Lett. Pol., vol. 3, no. 4, pp. pp. 144–146, Dec. 2011.

Issue

Vol. 3 No. 4 (2011)

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Articles

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